I am not familiar with these characters or series this is from, so the impact of the piece is lost on me. Despite that, however, I can tell you took the time to try and detail the monster; this makes the creature more believable as a experiment, where featuring the individual segments of the creature is essential to giving the necessary impression. The dark, sinister atmosphere helps add to the abomination.
While the creature itself is detailed, I would have liked to see more detail in the structures and in the character standing in the background; as is, the picture focuses almost too much on the creature, and not on the place it was created or held captive.
Overall, the effort is there and recognizable, and I'm sure fans of the series can appreciate it even more for what it is. Good job.